#6: Christina Applegate Now
Applegate went on to build one of the most respected careers of any sitcom alum. She’s starred in everything from Anchorman to Samantha Who? and Dead to Me, where her sharp emotional range earned critical acclaim. Her chemistry with co-star Linda Cardellini made the Netflix series a standout.

In recent years, she’s faced multiple sclerosis with remarkable grace, using her platform to raise awareness while stepping back from new projects. Her bravery and humor remain intact — the same energy that made Kelly Bundy unforgettable now shines through in her honesty and resilience.
